今月の研究者

田端 実

田端 実

キャリア
私は1999年に東京大学を卒業後、国内で一般外科と心臓外科の研修を積みました。研修医1年目のときに東大の先生方のご指導のもと高安病頸動脈瘤の手術症例をまとめて、英文論文を発表することができました。それ以来、自分たちの手術が患者さんや世の中に役立っているのか検証したいという思いが生じ、アウトカム臨床研究に興味を持ちました。
2004年には渡米してハーバード大学の教育病院であるBrigham and Women’s Hospitalのクリニカルフェローとなり、毎日心臓手術に明け暮れながらも、週末などに臨床研究論文を書いていました。そのうち臨床研究の方法論をしっかり学びたいと考え、2006年にハーバード公衆衛生大学院に入学し、臨床疫学や生物統計学、大規模データベース研究の方法論などを中心に学びました。この間多くの臨床論文を発表し、米国の心臓手術54万例のデータを解析したアウトカム研究論文も仕上げました。
その後、ニューヨークのコロンビア大学病院とベルギーのOLVクリニックで内視鏡下手術を含む低侵襲心臓手術を習得し、2009年より榊原記念病院、2013年より東京ベイ・浦安市川医療センターに勤務し、2019年までに3,000例以上の心臓・大血管手術を執刀してきました。2019年4月に虎の門病院循環器センター外科特任部長に就任しました。

研究分野
 私の臨床面でのメインワークとなっているのが非常に小さな創で行う内視鏡下心臓手術とカテーテル心臓弁膜症治療です。どちらも身体への負担が小さな治療ですが弱点があることも事実です。それに伴い研究面では、これらの低侵襲治療がどのような患者さんに向いておりどのような患者さんに向いていないか、どれほど患者さんの生活の質改善に役立っているか、医療コストなどの面で世の中にどれほど貢献できるかということを検証する臨床研究を主に行っています。
 そのほかには、退院後の術後合併症を早期発見するためのアプリや自ら特許を取得したカテーテル人工弁の開発にも携わっています。

今後の抱負
 臨床と研究の両方において、これまでにないものを生み出していくことを常に目指しています。

発表・論文

論文実

1. Noguchi M, Tabata M, Obunai K, Shibayama K, Ito J, Watanabe H, Yashima F, Watanabe Y, Naganuma T, Araki M, Yamanaka F, Shirai S, Ueno H, Mizutani K, Higashimori A, Takagi K, Tada N, Yamamoto M, Hayashida K. Clinical outcomes of transcatheter aortic valve implantation (TAVI) in nonagenarians from the optimized catheter valvular intervention- TAVI registry. Catheter Cardiovasc Interv. 2020(Epub ahed of print)

2. Inohara T, Vemulapalli S, Kohsaka S, Yashima F, Watanabe Y, Shirai S, Tada N, Araki M, Naganuma T, Yamanaka F, Ueno H, Tabata M, Mizutani K, Higashimori A, Takagi K, Yamamoto M, Shimizu H, Fukuda K, Hayashida K; OCEAN-TAVI Investigators. Appropriateness of Transcatheter Aortic Valve Replacement; Insight From the OCEAN-TAVI Regestry. Circ Cardiovasc Qual outcomes. 2020;13(4):e006146

3. Nakanaga H, Tabata M. Modified commissural placation in mitral valve repair for commissural prolapsed. Gen Thorac Cardiovasc Surg. 2020 Feb.(Epub ahead of print)

4. Tokuda T, Yamamoto M, Kagase A, Koyama Y, Otsuka T, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y. Importance of combined assessment of skeletal muscle mass and density by computed tomography in predicting clinical outcomes after transcatheter aortic valve replacement. Int J Cardiovasc Imaging. 2020 ;36(5):929-938

5. Inomata M, Shiroshita H, Uchida H, Bandoh T, Akira S, Yamaguchi S, Kurokawa Y, Seki Y, Eguchi S, Wada N, Takiguchi S, Ieiri S, Endo S, Iwazaki M, Sato Y, Tamaki Y, Kitamura K, Tabata M, Kanayama H, Mimata H, Hasegawa T, Takahashi H, Onishi K, Uemura T, Hashizume M, Matsumoto S, Kitano S, Watanabe M. Current status of endoscopic surgery in Japan: The 14th National Survey of Endoscopic Surgery by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2020;13(1):7-18

6. Tabata M, Nishida H, Watanabe S, Uchimuro T, Takanashi S. Interscallop indentation closure as an adjunctive technique in mitral valve repair for degenerative mitral valve disease. Gen Thorac Cardiovasc Surg. 2020;68(3);233-239

7. Yoshijima N, Yanagisawa R, Hase H, Tanaka M, Tsuruta H, Shimizu H, Fukuda K, Naganuma T, Mizutani K, Araki M, Tada N, Yamanaka F, Shirai S, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Yamamoto M, Hayashida K; OCEAN-TAVI investigators. Update on the clinical impact of mild aortic regurgitation after transcatheter aortic implantation: Insights from the Japanese multicenter OCEAN-TAVI registry. Catheter Cardiovasc Interv. 2020;95(1):35-44

8. Nakanaga H, Matsumoto S, Tabata M. Papillary fibroelastoma entangled with tendinous chords: gap between echocardiographic and operative findings. Int J Cardiovasc Imaging. 2020;36(3):457-458

9. Matsushita A, Tabata M, Mihara W, Shimamoto T, Komiya T, Takanashi S, Tobaru T, Nakao T, Nakamura S, Sato Y. Risk score system for late aortic events in patients with uncomplicated type B aortic dissection. J Thorac Cardiovasc Surg. 2020;159(6):2173-2183

10. Koyama Y, Yamamoto M, Kagase A, Tsujimoto S, Kano S, Shimura T, Hosoba S, Watanabe Y, Tada N, Naganuma T, Araki M, Yamanaka F, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Shirai S, Hayashida K. Prognostic impact and periprocedural complications of chronic steroid therapy in patients following transcatheter aortic valve replacement: Propensity-matched analysis from the Japanese OCEAN registry. Catheter Cardiovasc Interv. 2020;95(4):793-802

11. Tanaka M, Yanagisawa R, Yashima F, Arai T, Jinzaki M, Shimizu H, Fukuda K, Watanabe Y, Naganuma T, Shirai S, Araki M, Tada N, Yamanaka F, Higashimori A, Takagi K, Ueno H, Tabata M, Mizutani K, Yamamoto M, Hayashida K; OCEAN-TAVI investigators. Previously implanted mitral surgical prosthesis in patients undergoing transcatheter aortic valve implantation: Procedural outcome and morphologic assessment using multidetector computed tomography. PLoS One. 2019;14(12):e0226512

12. Hioki H, Watanabe Y, Kozuma K, Kawashima H, Nagura F, Nakashima M, Kataoka A, Yamamoto M, Naganuma T, Araki M, Tada N, Shirai S, Yamanaka F, Higashimori A, Mizutani K, Tabata M, Takagi K, Ueno H, Hayashida K. The MAGGIC risk score predicts mortality in patients undergoing transcatheter aortic valve replacement: sub-analysis of the OCEAN-TAVI registry. Heart Vessels. 2019;34(12):1976-1983

13. Kato N, Shibayama K, Omori N, Hoshina M, Makihara Y, Okumura H, Tabata M, Obunai K, Hirao K, Pellikka PA, Watanabe H. Impact of transcatheter aortic valve replacement on hemodynamic status in patients with aortic stenosis and mitral stenosis: Doppler echocardiographic study. J Cardiol. 2019;74(6):532-538

14. Yamamoto M, Kagase A, Shimura T, Koyama Y, Tsujimoto S, Kano S, Hosoba S, Tada N, Yamanaka F, Naganuma T, Araki M, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Hayashida K; OCEAN-TAVI investigators. Percutaneous aortic valve intervention in patients scheduled for noncardiac surgery: A Japanese multicenter study. Cardiovasc Revasc Med. 2019:51553-8389(19):30648-7(online ahead of print)

15. Yamamoto M, Watanabe Y, Tada N, Naganuma T, Araki M, Yamanaka F, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Shirai S, Hayashida K; OCEAN-TAVI investigators. Transcathter aortic valve replacement outcomes in Japan: Optimized Catheter Valvular Intervention(OCEAN) Japanese multicenter registry. Cardiovasc Revasc Med. 2019;20(10):843-851

16. Ito J, Tabata M. How to implant a prosthetic valve in the aortic and mitral valve positions. Kyobu Geka. 2019;72(10):789-793

17. Katada Y, Tabata M, Nakanaga H, Takahashi A, Irie Y, Shimokawa T. Transcatheter plug occlusion for various complications after cardiac/thoracic aortic surgery. J Cardiovasc Surg(Torino). 2019;60(4):539-542

18. Nagura F, Kataoka A, Hara M, Kozuma K, Watanabe Y, Nakashima M, Hioki H, Kawashima H, Nara Y, Shirai S, Tada N, Araki M, Naganuma T, Yamanaka F, Ueno H, Tabata M, Mizutani K, Higashimori A, Takagi K, Yamamoto M, Hayashida K; OCEAN-TAVI investigators. Association between valvuloarterial impedance after transcatheter aortic valve implantation and 2-year mortality in elderly patients with severe symptomatic aortic stenosis: the OCEAN TAVI registry. Heart Vessels. 2019;34(6):1031-1039

19. Nara Y, Kataoka A, Watanabe Y, Makoto N, Hioki H, Kawashima H, Fukuko N, Kozuma K, Shirai S, Tada N, Araki M, Naganuma T, Yamanaka F, Ueno H, Tabata M, Mizutani K, Higashimori A, Takagi K, Yamamoto M, Hayashida K. Prognostic impact of postprocedure stroke volume in patients with low-gradient aortic stenosis. Open Heart. 2019;24;6(1):e000988

20. Shiroshita H, Inomata M, Bandoh T, Uchida H, Akita S, Hashizume M, Yamaguchi S, Eguchi S, Wada N, Takiguchi S, Ieiri S, Endo S, Iwazaki M, Tamaki Y, Tabata M, Kanayama H, Mimata H, Hasagawa T, Onishi K, Yanaga K, Morikawa T, Terachi T, Matsumoto S, Yamashita Y, Watanabe M. Endoscopic surgery in Japan: The 13 national survey (2014-2015) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2019;12(1):7-18

21. Kawano Y, Tabata M. Surgical devices for Minimally Invasive Cardiac Surgery(MICS). Kyobu Geka. 2018;71(10):788-793

22. Shimura T, Yamamoto M, Kano S, Hosoba S, Sago M, Kagase A, Koyama Y, Tsujimoto S, Otsuka T, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Hayashida K; OCEAN‐TAVI Investigators. Patients refusing transcatheter aortic valve replacement even once have poore clinical outcomes. J Am Heart Assoc. 2018; 18;7(18):e009195

23. Yanagisawa R, Tanaka M, Yashima F, Arai T, Kohno T, Shimizu H, Fukuda K, Naganuma T, Mizutani K, Araki M, Tada N, Yamanaka F, Shirai S, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Yamamoto M, Hayashida K. Frequency and Consequences of Cognitive Impairmentin Patients Underwent Transcatheter Aortic Valve Implantation. Am J Cardiol. 2018;122(5):844-850

24. Mizutani K, Hara M, Nakao M, Okai T, Kajio K, Murakami T, Shibata T, Yoshiyama M, Naganuma T, Yamanaka F, Higashimori A, Tada N, Takagi K, Araki M, Ueno H, Tabata M , Shirai S, Watanabe Y, Yamamoto M, Hayashida K. Is elevation of N-terminal pro-B-type natriuretic peptide at discharge associated with 2-year composite endpoint of all-cause mortality and heart failure hospitalization after transcatheter aortic valve implantation? Insights from a multicentre prospective OCEAN registry inJapan. BMJ Open. 2018;8(8):e021468

25. Kawashima H, Watanabe Y, Kozuma K, Kataoka A, Nakashima M, Hioki H, Nagura F, Nara Y, Shirai S, Tada N, Araki M, Naganuma T, Yamanaka F, Ueno H, Tabata M, Mizutani K, Higashimori A, Takagi K, Yamamoto M, Hayashida K; OCEAN-TAVI Investigators. Comparison of Midterm outcomes of transcatheter aortic valve implantation in patients with and without previous coronary artery bypass grafting. Heart Vessels. 2018;33(10):1229-1237

26. Hioki H, Watanabe Y, Kozuma K, Yamamoto M, Naganuma T, Araki M, Tada N, Shirai S, Yamanaka F, Higashimori A, Mizutani K, Tabata M, Takagi K, Ueno H, Hayashida K; OCEAN-TAVI Investigators. Effect of Serum C-Reactive Protein Level on Admission to Predict Mortality After Transcatheter Aortic Valve Implantation. Am J Cardiol. 2018 Jul 15;122(2):294-301

27. Shibata K, Yamamoto M, Kano S, Koyama Y, Shimura T, Kagase A, Yamada S, Kobayashi T, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Otsuka T, Hayashida K;on the behalf of OCEAN-TAVI investigators. Importance of Geriatric Nutritional Risk Index assessment in patients undergoing transcatheter aortic valve replacement. Am Hert J. 2018;202:68-75

28. Hioki H, Watanabe Y, Kozuma K, Yamamoto M, Naganuma T, Araki M, Tada N, Shirai S, Yamanaka F, Higashimori A, Mizutani K, Tabata M, Takagi K, Ueno H, Hayashida K; OCEAN-TAVI Investigators. Risk stratification using lean body mass in patients undergoing transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2018;92(7):1365-1373

29. Hibino M, Katada Y, Shibayama K, Obunai K, Watanabe H, Kawano Y, Watanabe S, Tabata M. Recurrent aortic root pseudoaneurysm after transcatheter occlusion-A word of caution. J Card Surg. 2018 Apr. 33(4):190-3

30. Miyasaka M, Tada N, Taguri M, Kato S, Enta Y, Otomo T, Hata M, Watanabe Y, Naganuma T, Araki M, Yamanaka F, Shirai S, Ueno H, Mizutani K, Tabata M, Higashimori A, Takagi K, Yamamoto M, Hayashida K, OCEAN-TAVI Investigators. Incidence, Predictors, and Clinical Impact of Prosthesis-Patient Mismatch Following Transcatheter Aortic Valve Replacement in Asian Patients: The OCEAN-TAVI Registry. JACC Cardiovasc Interv. 2018 Apr. 23;11(8):771-780

31. Tabata M. Transapical approach in transcatheter cardiovascular interventions. Gen Thorac Cardiovasc Surg. 2018 Apr;66(4):185-191

32. Yamawaki M, Araki M, Ito T, Honda Y, Tokuda T, Ito Y, Ueno H, Mizutani K, Tabata M, Higashimori A, Tada N, Takagi K, Yamanaka F, Naganuma T, Watanabe Y, Yamamoto M, Shirai S, Hayashida K. OCEAN-TAVI Registry. Ankle-brachial pressure index as a predictor of the 2-year outcome after transcatheter aortic valve replacement: data from the Japanese OCEAN-TAVI Registy. Heart Vessels. Heart Vessels. 2018 Jun;33(6):640-650

33. Nishi T, Shibayama K, Tabata M, Kato N, Noguchi M, Okumura H, Kawano Y, Nakatsuka D, Obunai K, Kobayashi Y, Watanabe H. Accuracy and usefulness of Aortic annular measurement using real-time three-dimensional transesophageal echocardiography. Comparion with direct surgical sizing. J Cardiol. 2018;71(3);230-6.

34. Kawano Y, Kanaoka Y, Hiraiwa N, Nakatsuka D, Tabata M. Emergency thoracic endovascular aortic repair with celiac artery coverage in hereditary hemorrhagic telagiectasia. J Vasc Surg Cases Innov Tech. 2017 25;3(2):57-9

35. Shimura T, Yamamoto M, Kano S, Kagase A, Kodama A, Koyama Y, Otsuka T, Kohsaka S, Tada N, Yamanaka F, Naganuma T, Araki M, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Watanabe Y, Hayashida K. Impact of Frailty markers on outcomes after transcatheter aortic valve replacement: insights from a Japanese multicenter registry. Ann Cardiothorac Surg. 2017;6(5):532-537

36. Nakatsuka D, Tabata M. Transappical approach for transcatheter aortic valve implantation. Ann Cardiothorac Surg. 2017;6(5):553-554

37. Noguchi M, Nakai T, Kawano Y, Shibayama K, Obunai K, Tabata M, Watanabe H. Delayed right ventricular defibrillation lead perforation presenting as cardiac tamponade and treated surgically. Clin Case Rep. 2017;2;5(4):458-462

38. Nishida H, Tabata M, Fukui T, Sato Y, Kin H, Takanashi S. A systematic approach to improve the outcomes of type A aortic dissection. J Thorac Cardiovasc Surg. 2017 ;154(1):89-96

39. Maimaituxun G, Shimabukuro M, Salim HM, Tabata M, Yuji D, Morimoto Y, Akasaka T, Matsuura T, Yagi S, Fukuda D, Yamada H, Soeki T, Sugimoto T, Tanaka M, Takanashi S, Sata M. Gender-linked impact of epicardial adipose tissue volume in patients who underwent coronary artery bypass graft surgery or non-coronary valve surgery. PLoS One. 2017;8;12(6):e0177170

40. Mizutani K, Hara M, Iwata S, Murakami T, Shibata T, Yoshiyama M, Naganuma T, Yamanaka F, Higashimori A, Tada N, Takagi K, Araki M, Ueno H, Tabata M, Shirai S, Watanabe Y, Yamamoto M, Hayashida K. Elevation of B-Type Natriuretic Peptide at Discharge is Associated With 2-Year Mortality After Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis: Insights From a Multicenter Prospective OCEAN-TAVI (Optimized Transcatheter Valvular Intervention-Transcatheter Aortic Valve Implantation) Registry. J Am Heart Assoc. 2017;14;6(7):e00611

41. Noguchi M, Tabata M, Ito J, Nakatsuka D, Kwano Y, Shibayama K, Watanabe H, Obunai K. Successfully Treated Nonocclusive Mesenteric Ischemia After Transcatheter Aortic Valve Replacement. Ann Thorac Surg. 2017;103;e171-3

42. Nishida H, Nakatsuka D, Kwano Y, Hiraiwa N, Takanashi S, Tabata M. Outcomes of Totally Endoscopic Atrial Septal Defect Closure Using a Glutaraldehyde-Treated Autologous Pericardial Patch. Circ J. 2017 Apr 25;81(5):689-93

43. Hosoda T, Iguchi N, Cho Y, Inoue M, Murakami T, Tabata M, Takanashi S, Tomoike H. The proliferative potential of human cardiac stem cells was unaffected after a long-term crvopreservation of tissue blocks. Ann Transl Med. 2017;5;41

44. Naganuma T, Kawamoto H, Takagi K, Yabushita H, Mitomo S, Watanabe Y, Shirai S, Araki M, Tada N, Yamanaka F, Yamamoto M, Onishi H, Nakamura S, Higashimori A, Tabata M, Mizutani K, Ueno H, Hayashida K. Can we perform rotational atherectomy in patients with severe aortic stenosis? Substudy from the OCEAN TAVI Registry. Cardiovasc Revasc Med. 2017 Jul-Aug;18(5):356-60

45. Bandoh T, Shiraishi N, Yamashita Y, Terachi T, Hshizume M, Akira S, Morikawa T, Kitagawa Y, Yanaga K, Endo S, Onishi K, Takiguchi S, Tamaki Y, Hasagawa T, Mimata H, Tabata M, Yozu R, Inomata M, Matsumoto S, Kitano S, Watanabe M. Endosopic surgery in Japan: The 12th national survey(2012-2013) by the Japan Society for Endoscopic Surgery. Asian J Endosc Surg. 2017;10(4):345-53

46. Kano S, Yamamoto M, Shimura T, Kagase A, Tsuzuki M, Kodama A, Koyama Y, Kobayashi T, Shibata K, Tada N, Naganuma T, Araki M, Yamanaka F, Shirai S, Mizutani K, Tabata M, Ueno H, Takagi K, Higashimori A, Otsuka T, Watanabe Y, Hayashida K. Gait speed can predict advanced clinical outcomes in patients who undergo transcatheter aortic valve replacement: Insights from a Japanese multicenter registry. Circ Cardiovasc Interv. 2017;10(9):e005088

47. Katada Y, Ito J, Shibayama K, Nakatsuka D, Kawano Y, Watanabe H, Tabata M. Transapical Transcatheter Closure of the Pseudoaneurysm in the Left Ventricular Outflow Tract After Aortic Valve Replacement. JACC Cardiovasc Interv. 2016;9;e181-3

48. Noguchi M, Obunai K, Tabata M, Watanabe H. Successful Retrieval of the Atherosclerotic Plaque in the Left Main Coronary Artery Using a Balloon Thrombectomy. JACC Cardiovasc Interv. 2016;9:1966-7

49. Kawano Y, Tabata M, Nakatsuka D, Hiraiwa N. A Novel Approach for Emergency Repair of Intraoperative Type A Aortic Dissection Through a Left Thoracotomy. Ann Thorac Surg 2016;102:e147-9

50. Tabata M, Nakatsuka D, Nishida H, Takanashi S, Hiraiwa N, Kawano Y. A Simple Nonresectional Technique for Degenerative Mitral Regurgitation With a Very Large Posterior Leaflet: Chordal Foldoplasty. Ann Thorac Surg 2016;101:e179-81

51. Nishida H, Tabata M, Fukui T, Takanashi S. Surgical Strategy and Outcome for Aortic Root in Patients Undergoing Repair of Acute Type A Aortic Dissection. Ann Thorac Surg 2016;101:1464-9.

52. Matsushita A, Fukui T, Tabata M, Sato Y, Takanashi S. Preoperative characteristics and surgical outcomes of acute intramural hematoma involving the ascending aorta: A propensity score-matched analysis. J Thorac Cardiovasc Surg 2016;151:351-8.

53. Tabata M, Hiraiwa N, Kawano Y, Nakatsuka D, Hoshino S. A simple effective and inexpensive technique for exposure of papillary muscles in minimally invasive mitral valve repair.: Wakka technique. Ann Thorac Surg 2015;100:e59-61

54. Fukui T, Tabata M, Morita S, Takanashi S. Gender difference in patients undergoing surgery for acute type A aortic dissection. J Thorac Cardiovasc Surg 2015;150:581-7

55. Kurokawa H, Misumi I, Honda T, Usuku H, Yasuda H, Kaikita K, Hokimoto S, Ogawa H, Nakatsuka D, Tabata M. Resonant cardiac chamber with diastolic thrill. J Echocardiogr. 2015;13(2):69-71

56. Kasegawa H, Tabata M, Shimizu A, Naito K, Fukui T, Takanashi S. A new type of mitral valve operation using a novel stentless mitral valve made from autologous percardioum for unrepairable valve. J Heart Valve Dis 2015;24:53-6

57. Nishigawa K, Fukui T, Tabata M, Takanashi S. V-composite grafting using the right internal thoracic artery grafts anastomosed to aroto-coronary bypass grafts. Eur J Cardiothorac Surg 2015;48:753-7

58. Takashima A, Shimabukuro M, Tabata M, Fukuda D, Uematsu E, Ishibashi-Ueda H, Takanashi S, Sata M. Histopathological heterogeneity of in-stent restenosis in four coronary endarterectomy specimens. Cardiovasc Pathol 2015;24:194-7.

59. Shimizu A, Kasegawa H, Tabata M, Fukui T, Takanashi S. Long-Term Outcomes of Mitral Valve Repair for Isolated Commissural Prolapse: Up to 17-Year Experience. Ann Thorac Surg 2015;99:43-7.

60. Nishi T, Shibayama K, Tabata M, Kamio T, Noguchi M, Okumura H, Kawano Y, Nakatsuka D, Hiraiwa N, Obunai K, Kobayashi Y, Watanabe H. A case of right ventricular diastolic dysfunction due to a large hematoma posterior to the left ventricle. J Cardiol Cases. 2015;12(1):8-11

61. Fukui T, Tabata M, Takanashi S. Long-term outcomes after off-pump coronary artery bypass grafting in left ventricular dysfunction. Ann Thorac Cardiovasc Surg. 2014;20(2):143-9

62. Nishida H, Tabata M, Fukui T, Takanashi S. Mycotic coronary artery aneurysm and mitral valve regurgitation caused by infectious endocarditis. J Card Surg. 2014;29:797-8

63. Tabata M, Kasegawa H, Fukui T, Shimizu A, Sato Y, Takanashi S. Long-term outcomes of artificial chordal replacement with tourniquet technique in mitral valve repair: A single-center experience of 700 cases. J Thorac Cardiovasc Surg 2014;148:2033-8

64. Fukui T, Tabata M, Tobaru T, Asano R, Takanashi S, Sumiyoshi T. Early and long-term outcomes of coronary artery bypass grafting and percutaneous coronary intervention in patients with left main disease: single-center results of multidisciplinary decision making. Gen Thorac Cardiovasc Surg 2014;62:301-7

65. Yan TD, Tian DH, Lemaire SA, Misfeld M, Elefteriades JA, Chen EP, Chad Hughes G, Kazui T, Griepp RB, Kouchoukos NT, Bannon PG, Underwood MJ, Mohr FW, Oo A, Sundt TM, Bavaria JE, Di Bartolomeo R, Di Eusanio M, Roselli EE, Beyersdorf F, Carrel TP, Corvera JS, Della Corte A, Ehrlich M, Hoffman A, Jakob H, Matalanis G, Numata S, Patel HJ, Pochettino A, Safi HJ, Estrera A, Perreas KG, Sinatra R, Trimarchi S, Sun LZ, Tabata M, Wang C, Haverich A, Shrestha M, Okita Y, Coselli J. The ARCH Projects: design and rationale (IAASSG 001). Eur J Cardiothorac Surg 2014;45:10-6.

66. Uchimuro T, Tabata M, Saito K, Shibayama K, Watanabe H, Fukui T, Shimokawa T, Kasegawa H, Takanashi S. Post-repair coaptation length and durability of mitral valve repair for posterior mitral valve prolapse. Gen Thorac Cardiovasc Surg 2014;62:221-7

67. Fukui T, Bando K, Tanaka S, Uchimuro T, Tabata M, Takanashi S. Early and mid-term outcomes of combined aortic valve replacement and coronary artery bypass grafting in elderly patients. Eur J Cardiothorac Surg 2014;45:335-40

68. Sasaki K, Fukui T, Tabata M, Takanashi S. Early pseudoaneurysm formation after the sutureless technique for left ventricular rupture due to acute myocardial infarction. Gen Thorac Cardiovasc Surg 2014;62:171-4.

69. Matsushita A, Tabata M, Fukui T, Sato Y, Matsuyama S, Shimokawa T, Takanashi S. Outcomes of contemporary emergency open surgery for type A acute aortic dissection in elderly patients. J Thorac Cardiovasc Surg 2014;147:290-4.

70. Tabata M, Shibayama K, Watanabe H, Sato Y, Fukui T, Takanashi S. Simple interrupted suturing increases valve performance after aortic valve replacement with a small supra-annular bioprosthesis. J Thorac Cardiovasc Surg 2014;147:321-5

71. Shibayama K, Watanabe H, Sasaki S, Mahara K, Tabata M, Fukui T, Takanashi S, Sumiyoshi T, Tomoike H, Shiota T. Impact of regurgitant orifice height for mechanism of aortic regurgitation. JACC Cardiovasc Imaging 2013;6:1347-9

72. Tabata M, Fukui T, Takanashi S. Do minimally invasive approaches improve outcomes of heart valve disease? Circulation J 2013;77:2232-9

73. Sasaki S, Watanabe H, Shibayama K, Mahara K, Tabata M, Fukui T, Tobaru T, Takanashi S, Sumiyoshi T, Tomoike H. Three-Dimensional Transesophageal Echocardiographic Evaluation of Coronary Involvement in Patients with Acute Type A Aortic Dissection. J Am Soc Echocardiogr 2013;26:837-45.

74. Manabe S, Kasegawa H, Fukui T, Tabata M, Shinozaki T, Shimokawa T, Takanashi S. Do Semi-Rigid Prosthetic Rings Affect Left Ventricular Function After Mitral Valve Repair? Circ J 2013;77:2038-42.

75. Shimabukuro M, Hirata Y, Tabata M, Dagvasumberel M, Sato H, Kurobe H, Fukuda D, Soeki T, Kitagawa T, Takanashi S, Sata M. Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis. Arterioscler Thromb Vasc Biol 2013;33:1077-84.

76. Kato Y, Fukui T, Tabata M, Takanashi S. Successful infarct exclusion for postinfarction left ventricular free wall rupture. Interact cardiovasc Thorac Surg 2013;16:900-2

77. Tian Z, Miyata K, Tazume H, Sakaguchi H, Kadomatsu T, Horio E, Takahashi O, Komohara Y, Araki K, Hirata Y, Tabata M, Takanashi S, Takeya M, Hao H, Shimabukuro M, Sata M, Kawasuji M, Oike Y. Perivascular adipose tissue-secreted angiopoietin-like protein 2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury. J Mol Cell Cardiol 2013;57:1-12

78. Saji M, Murai T, Tobaru T, Tabata M, Takanashi S, Takayama M. Autopsy finding of the Sapien XT valve from a patient who died suddenly after transcatheter aortic valve replacement. Cardiovasc Interv Ther 2013;28:267-71

79. Tabata M, Kasegawa H, Suzuki T, Watanabe H, Fukui T, Takanashi S, Ono M. Long-term outcomes of early surgery for asymptomatic severe chronic mitral regurgitation. J Heart Valv Dis 2013;22:354-60.

80. Manabe S, Kasegawa H, Fukui T, Tabata M, Shinozaki T, Shimokawa T, Takanashi S. Infuluence of left ventricular function on development of systolic anterior motion after mitral valve repair. J Thorac Cardiovasc Surg 2013;146:291-5

81. Fukui T, Tabata M, Morita S, Takanashi S. Early and long-term outcomes of coronary artery bypass grafting in patients with acute coronary syndrome versus stable angina pectoris. J Thorac Cardiovasc Surg 2013;145:1577-83.

82. Ozawa K, Watanabe H, Asano R, Tobaru T, Takamisawa I, Tabata M, Fukui T, Shimizu J, Takanashi S, Takayama M, Tomoike H. A case of osteopetrosis with severe aortic stenosis treated by transcatheter aortic valve implantation. J Cardiol Cases. 2013;8(3):113-5

83. Manabe S, Kasegawa H, Fukui T, Tabata M, Shimokawa T, Takanashi S. Morphological analysis of systolic anterior motion after mitral valve repair. Interact Cardiovasc Thorac Sung 2012;15:235-9

84. Manabe S, Shimokawa T, Fukui T, Tabata M, Takanashi S. Impact of papillary muscle approximation on mitral valve configuration in the surgical correction of ischemic mitral regurgitation. Thorac Cardiovasc Surg 2012;60:269-74

85. Matsuyama S, Tabata M, Shimokawa T, Matsushita A, Fukui T, Takanashi S. Outcomes of total arch replacement with stepwise distal anastomosis technique and modified perfusion strategy. J Thorac Cardiovasc Surg 2012;143:1377-81.

86. Myers PO, Tabata M, Shekar PS, Couper GS, Khalpey ZI, Aranki SF. Extensive endarterectomy and reconstruction of the left anterior descending artery: early and late outcomes. J Thorac Cardiovasc Surg 2012;143:1336-40

87. Matsushita A, Manabe S, Tabata M, Fukui T, Shimokawa T, Takanashi S. Efficacy and pitfalls of transapical cannulation for the repair of acute type A aortic dissection. Ann Thorac Surg 2012;93:1905-9.

88. Shibayama K, Watanabe H, Tabata M, Sasaki S, Fukui T, Umemura J, Takanashi S, Sumiyoshi T. Impact of ejection fraction on long-term outcome after elective aortic valve replacement in octogenarians with aortic stenosis. Circ J 2012;76:1761-7

89. Yamamoto K, Fukui T, Matsuyama S, Tabata M, Aramoto H, Takanashi S. Prior cardiac and thoracic aortic surgery as a complication risk factor for abdominal aortic aneurysm repair. Circ J 2012;76:1380-4.

90. Fukui T, Tabata M, Morita S, Takanashi S. Sequential free right internal thoracic artery grafting for multivessel coronary artery bypass grafting. J Thorac Cardiovasc Surg, 2012 ;143:236-7

91. Fukui T, Yamada M, Tabata M, Takanashi S. Thoracoabdominal aortic aneurysm repair with patent gastroepiproic artery graft. J Thorac Cardiovasc Surg 2012;143:236-7

92. Uchimuro T, Fukui T, Matsuyama S, Tabata M, Takanashi S. Mitral valve replacement in dextrocardia and situs inversus. Kyobu Geka. 2012;65(10):858-61

93. Fukui T, Tabata M, Matsuyama S, Takanashi S. Graft selection in elderly patients undergoing coronary artery bypass grafting. Gen Thorac Cardiovasc Surg 2011;59:786-92

94. Hirata Y, Tabata M, Kurobe H, Motoki, Akaike M, Nishio C, et al. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol 2011;58:248-55

95. Fukui T, Shimokawa T, Tabata M, Takanashi S. Outcomes of total aortic arch replacement with coronary artery bypass grafting. Interact Cardiovasc Thorac Surg 2011;13:284-7

96. Shimokawa T, Kasegawa H, Katayama Y, Matsuyama S, Manabe S, Tabata M, Fukui T, Takanashi. Mechanisms of recurrent regurgitation after valve repair for prolapsed mitral valve disease. Ann Thorac Surg 2011;91:1433-8

97. Tabata M, Shimokawa T, Fukui T, Manabe S, Sato Y, Takanashi S. New uncoated vascular prosthesis reduces mediastinal tube drainage after thoracic aortic surgery. Ann Thorac Surg 2011;91:899-902.

98. Fukui T, Watanabe H, Aikawa M, Tsunoda Y, Tabata M, Takanashi S. Assessment of coronary flow velocity reserve by transthoracic Doppler echocardiography before and after coronary artery bypass grafting. Am J Cardiol 2011;107:1324-8.

99. Fukui T, Tabata M, Taguri M, Manabe S, Morita S, Takanashi S. Extensive reconstruction of the left anterior descending coronary artery with an internal thoracic artery graft. Ann Thorac Surg 2011;91:445-51.

100. Shibayama K, Watanabe H, Sasaki S, Tabata M, Fukui T, Kasegawa H, Umemura J, Takanashi S, Sumiyoshi T. The clinical value of real-time three-dimensional transesophageal echocardiography; The assessment of paravalvular leakage after prosthetic mitral valve replacement. J Echocardiog. 2011;9(2):77-8

101. Fukui T, Tabata M, Manabe S, Shimokawa T, Takanashi S. Graft selection and one-year patency rates in patients undergoing coronary artery bypass grafting. Ann Thorac Surg 2010;89:1901-5.

102. Iwata H, Sata M, Ando J, Fujita H, Morita T, Sawaki D, Takahashi M, Hirata Y, Takanashi S, Tabata M, Hirata Y, Nagai R. Impact of primitive cells in intracoronary thrombi on lesion prognosis: temporal analysis of cellular constituents of thrombotic material obtained from patients with acute coronary syndrome. Heart 2010;96:748-55.

103. Manabe S, Fukui T, Tabata M, Shimokawa T, Morita S, Takanashi S. Arterial graft deterioration one year after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2010;140:1306-11.

104. Fukui T, Tabata M, Manabe S, Shimokawa T, Shimizu J, Morita S, Takanashi S. Off-pump bilateral internal thoracic artery grafting in patients with left main disease. J Thorac Cardiovasc Surg 2010;140:1040-5

105. Manabe S, Fukui T, Shimokawa T, Tabata M, Katayama Y, Morita S, Takanashi S. Increased graft occlusion or string sign in composite arterial grafting or mildly stenosed target vessels. Ann Thorac Surg 2010;89:683-7.

106. Tanaka M, Tabata M, Shimokawa T, Takanashi S. The rupture of descending thoracic aorta due to the necrosis of aortic intimal sarcoma. Interact Cardiovasc Thorac Surg 2010;10:462-3

107. Matsushita A, Manabe S, Tabata M, Fukui T, Shimokawa T, Amano J, Takanashi S. Heterogeneous double cardiac tumor: myxoma concomitant with papillary fibroelastoma. J Card Surg 2010;25:35-7

108. Fukui T, Tabata M, Manabe S, Shimokawa T, Morita S, Takanashi S. Angiographic outcomes of right internal thoracic artery grafts in situ or as free grafts in coronary artery

109. Tabata M, Grab JD, Khalpey Z, Edwards F, O’Brien S, Cohn LH, Bolman RM. Prevalence and variability of Internal mammary artery grafts use in contemporary multivessel coronary artery bypass graft surgery: Analysis of the Society of Thoracic Surgeons database. Circulation 2009;120:935-40.

110. Tabata M, Takayama H, Bowdish ME, Smith CR, Stewart AS. Modified Bentall operation with bioprosthetic valved conduit. Ann Thorac Surg 2009;87:1969-70

111. Tabata M, Khalpey Z, Shekar PS, Cohn LH. Reoperative minimal access aortic valve surgery: Minimal mediastinal dissection and minimal injury risk. J Thorac Cardiovasc Surg 2008;136:1564-8

112. Tabata M, Khalpey Z, Cohn LH, Chen FY, Bolman RM, Rawn JD. Effect of preoperative statins in cardiac surgery patients without coronary artery disease. J Thorac Cardiovasc Surg 2008;136:1510-3

113. Tabata M, Ghanta RK, Shekar P, Cohn LH. Early and midterm results of folding valvuloplasty without leaflet resection. Ann Thorac Surg 2008;86:1388-90.

114. Tabata M, Shekar P, Couper G, Aranki SF. Early and late outcomes of multiple coronary endarterectomy. J Card Surg 2008;23:697-700.

115. Tabata M, Umakanthan R, Shekar P, Chen FY, Couper GS, Aranki SF, Cohn LH. Early and late outcomes of 1,000 minimally invasive aortic valve operations. Eur J Cardiothorac Surg 2008;33:537-41

116. Horai T, Fukui T, Tabata M, Takanashi S. Early and mid-term results of off-pump coronary artery bypass grafting in patients with end stage renal disease: surgical outcomes after achievement of complete revasularization. Interact Cardiovasc Thorac Surg 2008;7:218-21.

117. Fukui T, Takanashi S, Tabata M, Hosoda Y. Mild or moderate ischemic mitral regurgitation in patients undergoing off-pump coronary artery bypass grafting. J Card Surg 2007;22:480-5

118. Tabata M, Khalpey Z, Pirundini PA, Byrne ML, Cohn LH, Rawn JD.  Renoprotective effect of preoperative statins in coronary artery bypass grafting. Am J Cardiol 2007;100:442-4.

119. Tabata M, Umakanthan R, Khalpey Z, Couper GS, Aranki SF, Cohn LH, Shekar P. Conversion to full sternotomy during Minimal-access cardiac surgery: Reasons and results during a 9.5 year experience. J Thorac Cardiovasc Surg 2007;134:165-9.

120. Tabata M, Khalpey Z, Aranki S, Couper G, Cohn L, Shekar P. Minimal Access surgery of ascending and proximal arch of the aorta: a 9 year experience. Ann Thorac Surg 2007;84:67-72

121. Tabata M, Aranki SF, Fox JA, Couper GC, Cohn LH, Shekar PS. Minimally invasive aortic valve replacement in patients with left ventricular dysfunction. Asian Cardiovasc Thorac Ann 2007;15:225-228.

122. Tabata M, Cohn LH. Minimally invasive mitral valve repair with and without robotic technology in the elderly. Am J Geriatr Cardiol 2006;15(5):306-310

123. Tabata M, Takanashi S, Fukui F, Horai T, Hosoda Y. Emergency conversion in off-pump coronary artery bypass grafting. Interactive Cardiovasc Thorac Surg 2006;5:555-559

124. Tabata M, Takanashi S, Fukui F, Horai T, Uchimuro T, Kitabayashi K, Hosoda Y. Off-pump coronary artery bypass grafting in patients with renal dysfunction. Ann Thorac Surg 2004;78:2044-9

125. Tabata M, Kitayama J, Kanemoto H, Fukasawa T, Goto H, Taniwaka K. Autoimmune pancreatitis presenting as a mass in the head of the pancreas: a diagnosis to differentiate from cancer. Am Surg 2003;69(5):363-6.

126. Tabata M, Kitagawa T, Saito T, Uozaki H, Oshiro H, Miyata T, Shigematsu H. Extracranial carotid aneurysm in Takayasu’s arteritis. J Vasc Surg 2001;34:739-42.

Copyright © 2020 冲中記念成人病研究所 All Rights Reserved.